Table 2.

Daily use of AC supplement vs. use every 48 hours.

	Timepoint	Use of AC supplement every 48 hours			Use of AC supplement daily			Use of AC daily vs. use every 48 hours
		Mean ± SD	n	Treatment % change	Mean ± SD	n	Treatment % change
Collagen fragmentation	Week 0	6.23 ± 0.56	13		5.81 ± 1.0	48
	Week 12	5.57 ± 0.83	14	−10.6	3.22 ± 1.24	46	−44.6	p < 0.01
Elasticity R2	Week 0	0.721 ± 0.14	14		0.682 ± 0.10	48
	Week 12	0.855 ± 0.12	14	18.6	0.837 ± 0.11	48	22.7	p=0.68
Profilometry Rz	Week 0	140.2 ± 10.7	14		136.9 ± 11.0	48
	Week 12	122.7 ± 10.3	14	−12.5	110.1 ± 8.4	48	−19.7	p < 0.01
Skin even tone	Week 0	5.57 ± 1.02	14		5.6 ± 1.12	48
	Week 12	4.11 ± 0.96	14	−26.3	3.81 ± 1.08	48	−31.9	p=0.03

Descriptive and probability statistics are presented. The table shows the mean and standard deviation at baseline and week 12, and percent change from baseline for each measurement at week 12. Statistical significance of the comparison of supplement use daily vs. use every 48 hours is presented. A threshold of p ≤ 0.05 was applied in all cases.