Extended Data Fig. 6. Escape at key sites for each serum.

Logoplots showing XBB.1.5 spike escape at 16 highest escape sites for each of the 10 sera measured. Letter heights indicate the escape caused by mutation to that amino acid. Letters are colored light yellow to dark brown depending on mutation effect on ACE2 binding. Left: all mutations measured. Right: mutations accessible with a single-nucleotide substitution.