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. 2024 May 23;23(3):233–246. doi: 10.1007/s10689-024-00397-w

Table 2.

Heritability estimates for different models using all cancer types or PDAC as the dependent variable. Real scale is the observable scale of the trait versus the liability scale which is non-observable. Liability follows a standardized normal distribution that after a certain threshold triggers the illness

Dependent variable Heritability Liability scale Real scale
All cancer types Model I 0.99 [0.98–0.99] 0.55 [0.41–0.63]
Model II 0.39 [0.28–0.52] 0.22 [0.15–0.29]
Model III 0.21 [0.1–0.33] 0.1 [0.04–0.16]
Only PDAC (Model III) 500,000 iterations 0.27 [0.06–0.47] 0.07 [0.02–0.12]
Only PDAC (Model III) 600,000 iterations 0.27 [0.07–0.47] 0.07 [0.02–0.13]