Table 3.
Characteristics of cancers detected and not detected by each reading strategy
| Original screening | Reader study w/o AI | Reader study with AI | AI standalone | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| All | Recalled | Not recalled | Recalled | Not recalled | Recalled | Not recalled | Flagged | Not flagged | ||
| n | 379 | 232 | 147 | 307 | 72 | 284 | 95 | 261 | 118 | |
| Dense areaa | Mean cm2 | 36.7 | 33.9 | 44.1 | 35.5 | 41.8 | 35.5 | 40.1 | 35.3 | 39.7 |
| Percent densitya | Mean % | 24.5 | 22.7 | 27.4 | 23.4 | 29.4 | 23.3 | 28.0 | 23.4 | 26.9 |
| In situ only | % (n) | 10 (39) | 12 (29) | 7 (10) | 11 (35) | 6 (4) | 11 (32) | 7 (7) | 11 (29) | 9 (10) |
| Invasive < = 15 mm | % (n) | 42 (161) | 44 (102) | 40 (59) | 44 (134) | 38 (27) | 42 (119) | 44 (42) | 41 (106) | 47 (55) |
| Invasive > 15 mm | % (n) | 45 (170) | 42 (98) | 49 (72) | 44 (134) | 50 (36) | 45 (128) | 44 (42) | 48 (124) | 39 (46) |
| Missing information | % (n) | 2 (9) | 1 (3) | 4 (6) | 1 (4) | 7 (5) | 2 (5) | 4 (4) | 1 (2) | 6 (7) |
| Lymph node negative | % (n) | 66 (251) | 71 (164) | 59 (87) | 68 (208) | 60 (43) | 69 (196) | 58 (55) | 69 (179) | 61 (72) |
| Lymph node positive | % (n) | 27 (103) | 22 (51) | 35 (52) | 25 (77) | 36 (26) | 24 (68) | 37 (35) | 25 (66) | 31 (37) |
| Missing information | % (n) | 7 (25) | 7 (17) | 5 (8) | 7 (22) | 4 (3) | 7 (20) | 5 (5) | 6 (16) | 8 (9) |
aDense area and percent density were calculated by the Libra software package from University of Pennsylvania (https://www.med.upenn.edu/cbica/sbia/libra.html)