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. 2024 Jun 24;27:101139. doi: 10.1016/j.mtbio.2024.101139

Fig. 4.

Fig. 4

Micropolymers and associated plasticizers activating various pathways like Wnt/β-catenin signalling and NLRP3/caspase-1 pathway. PS-MPs induce oxidative stress leading to β-catenin release. In the nucleus, it binds to TCF/LEF, thus activating the signalling pathway [90]. PS-MPs also lead to pyroptosis and apoptosis of granulosa cells by activating the NLRP3/caspase-1 pathway through oxidative stress [185].