Table 1.
Baseline Patient Characteristics
| Characteristic | Variable | Mean±SD or N (%) |
|---|---|---|
| Demographics | Age, y | 40±17 |
| Women | 35 (54%) | |
| Height, cm | 174±12 | |
| BMI, kg/m2 | 25.3±7.3 | |
| Pathologic mutation | TGFBR1 | 18 (28%) |
| TGFBR2 | 20 (31%) | |
| SMAD3 | 11 (17%) | |
| TGFB2 | 11 (17%) | |
| TGFB3 | 5 (7%) | |
| Comorbidities | Hypertension | 17 (26%) |
| Aortic root replacement | 16 (25%) | |
| Type A aortic dissection | 10 (15%) | |
| Type B aortic dissection | 3 (5%) | |
| Cervical carotid tortuosity | Vessel length, mm | 206.6±42.4 |
| Tortuosity index | 0.262±0.131 | |
| Total absolute curvature | 11.13±5.76 | |
| RMS curvature | 0.212±0.188 |
BMI indicates body mass index; and RMS, root mean square.