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. 2024 Jun 11;13(12):e032888. doi: 10.1161/JAHA.123.032888

Figure 6. Upregulation of FSTL3 in remodeled RVs from patients with PAH and animal models.

Figure 6

A, Representative Western blots and corresponding quantifications of FSTL3 in dissected pulmonary arteries and RVs from CTRL (n=18–19) and patients with PAH (n=13–20). B, Representative Western blots and corresponding quantifications of FSTL3 in dissected PAs and RVs from CTRL (n=7–10) and monocrotaline‐injected (n=14–19) rats. C, Representative Western blot and corresponding quantification of FSTL3 in RVs from sham (n=7) and PAB‐subjected (n=17) rats. Protein expression was normalized to amido black. Scatter dot plots show individual values and mean±SEM. Statistical analyses were performed using Student's t test. *P<0.05 and **P<0.01. AB indicates amido black; CTRL, controls; FSTL3, follistatin‐like 3; MCT, monocrotaline; PA, pulmonary ateries; PAB, pulmonary artery banding; PAH, pulmonary arterial hypertension; and RV, right ventricle.