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. 2024 Jun 6;13(12):e032971. doi: 10.1161/JAHA.123.032971

Figure 2. Renal injury that develops in CKD rats after 12 weeks is partially improved by finerenone.

Figure 2

Kidney weight (A); GFR (B); and albuminuria (C). Representative light microphotographs (20× magnification) of rat kidney sections stained with Sirius red (D) and quantification of kidney fibrosis (E). Representative light microphotographs (20× magnification) of rat kidney sections stained with Masson Trichrome (F); quantification of tubular (G) and glomerular injury (H). ANOVA was used for statistical analysis, n=7–9. *P<0.05, **P<0.001, ***P<0.0001. CKD indicates chronic kidney disease; Fine, finerenone; and GFR, glomerular filtration rate.