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. Author manuscript; available in PMC: 2024 Jul 18.
Published in final edited form as: Sci Transl Med. 2020 Oct 28;12(567):eaaz4997. doi: 10.1126/scitranslmed.aaz4997

Figure 3. Antibody isotype kinetics in blood samples from macaque dams and infant offspring.

Figure 3.

Shown are the kinetics of IgM, IgA, and IgG antibodies against ZIKV envelope (E) protein and NS1 protein in blood samples from ZIKV-infected dams (A) and their infant offspring (B). Antibody binding to ZIKV protein-coated sensors was detected by surface plasmon resonance and is expressed as maximum relative units (Max RU). Max RU was calculated by multiplying the observed RU signal by dilution factors. The dashed line indicates the lower limit of detection for the assay. E, early gestational infection; L, late gestational infection; D, dam; I, infant offspring.