TABLE 2.

Descriptive statistics at enrolment for all randomized cats (n = 60) in this prospective dietary trial (MAGMA), grouped based on the allocated study diet (control PRD vs magnesium‐enriched PRD).

Variables (reference interval)	Control PRD (n = 33)		Magnesium‐enriched PRD (n = 27)		P‐value
	Median [25th, 75th Percentile]	n	Median [25th, 75th Percentile]	n
Age (years)	16.2 [13.3, 17.7]	33	15.2 [13.0, 17.0]	27	.87
BCS (“1‐3”, “4‐9”, n [%])	12 [36], 21 [64]	33	6 [22], 19 [76]	25	.31
MCS (“0”, “1”, “2”, “3”, n [%])	1 [3], 15 [45], 16 [48], 1 [3]	33	1 [4], 7 [28], 12 [48], 5[20]	25	.13
Weight (kg)	3.7 [3.2, 4.3]	33	4.2 [3.3, 4.7]	26	.52
Sex (female neutered, n [%])	17 [52]	33	10 [37]	27	.26
Albumin (2.5‐4.5 g/dL)	3.0 [2.8, 3.2]	33	3.1 [2.9, 3.2]	27	.77
ALP (≤ 60 U/L)	24 [20, 33]	33	26 [20, 33]	27	.88
ALT (5‐60 U/L)	54 [47, 65]	33	43 [34, 54]	27	.02
ALT (>60 U/L), n [%]	13 [39]	33	6 [22]	27	.16
Chloride (100‐124 mEq/L)	117 [114, 118]	20	117 [116, 119]	15	.5
Creatinine (0.23‐2 mg/dL)	2.41 [2.12, 2.74]	33	2.39 [2.1, 2.76]	27	.96
FGF23 a (56‐700 pg/mL)	418 [212, 801]	32	421 [225, 673]	26	.85
Glucose (54‐117 mg/dL)	114 [101, 128]	30	115 [101, 137]	25	.75
Venous HCO3 − (17‐24 mEq/L)	22.1 [19.4, 23.6]	28	21.6 [20, 23.3]	24	.41
Hypertension (controlled) (n [%])	7 [21]	33	6 [22]	27	.93
Ionized calcium (4.76‐5.48 mg/dL)	5.32 [5.2, 5.48]	28	5.28 [5.2, 5.4]	24	.36
PCV (30%‐45%)	34 [30, 37]	33	34 [30, 37]	27	.7
Venous pH (7.21‐7.44)	7.37 [7.34, 7.39]	28	7.38 [7.36, 7.39]	24	.23
Phosphate (2.79‐6.81 mg/dL)	3.99 [3.25, 4.4]	33	3.62 [3.25, 3.87]	27	.12
Potassium (3.5‐5.5 mEq/L)	4.03 [3.81, 4.20]	20	4.01 [3.70, 4.22]	25	.64
PTH a , b (2.6‐17.6 pg/mL)	10.3 [7.2, 16.4]	22	11.3 [6.6, 19.8]	20	.69
SBP (<160 mmHg)	132 [121, 143]	33	135 [121, 145]	27	.68
SDMA (1‐14 μg/dL)	18 [16, 21]	33	18 [15, 20]	27	.73
Sodium (145‐157 mEq/L)	154 [152, 155]	20	153 [152, 155]	15	.56
Total calcium (8.2‐11.8 mg/dL)	10.24 [9.84, 10.84]	33	10.12 [9.88, 10.64]	27	.31
Total magnesium (1.73‐2.57 mg/dL)	2.09 [1.87, 2.24]	33	2.04 [1.87, 2.19]	27	.51
Total protein (6.0‐8.0 g/dL)	8.0 [7.5, 8.4]	33	7.5 [7.3, 8.2]	27	.23
Urea (7.0‐27.7 mg/dL)	47.3 [42.6, 52.9]	20	44.8 [39.8, 56.0]	15	1
USG (≥1.035)	1.017 [1.015, 1.018]	17	1.015 [1.015, 1.018]	13	.54

Note: Significant difference between groups (P ≤ .05) are highlighted in bold.

Abbreviations: ALP, alkaline phosphatase; ALT, alanine aminotransferase; BCS, body condition score; FGF23, fibroblast growth factor‐23; HCO₃ ⁻, bicarbonate; MCS, muscle condition score; n, number of cats; PRD, phosphate‐restricted diet; PTH, parathyroid hormone; SBP, systolic blood pressure; SDMA, symmetric dimethylarginine; USG, urine specific gravity.

^a Baseline FGF23 and PTH were log‐transformed for comparison using independent samples t‐test and Mann‐Whitney U test, respectively.

^b Combined PTH results were obtained from immunoradiometric assay (n = 22) and 2‐site immunoenzymatic assay (n = 20).