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. 2024 Mar 16;9(4):e10659. doi: 10.1002/btm2.10659

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© 2024 The Authors. Bioengineering & Translational Medicine published by Wiley Periodicals LLC on behalf of American Institute of Chemical Engineers.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Extracellular levels of Apo(a) (a) and ApoB (b) in 24 h medium of hyper‐Lp(a) hepatocyte‐like cells (HLCs) (2D) (n = 6) and liver organoids (3D) (n = 3). Extracellular levels of Apo(a) (n = 18) (c) and ApoB (n = 14) (d) in 48 h medium of control (WT) and hyper‐Lp(a) (Lp(a)) liver organoids. Values are normalized against albumin production. Statistical significance was assessed using unpaired t test, with a p value cut‐off set at p < 0.05. *, p value <0.05; **, p value <0.01; ***, p value <0.001; ns, not significant.