FIGURE 1.

Adjuvants in licensed vaccines in the current clinical trial space. (a) The classification of unique vaccine formulations evaluated in clinical trials by adjuvant licensure status in which a unique vaccine formulation is defined by a distinct combination of adjuvant and antigen among the trial space. Each section displays the unique vaccine formulation count and that percentage of the whole. (b) The number of clinical trials that contain an adjuvant in a licensed vaccine displayed as the number of trials in which this adjuvant is utilized in a unique vaccine formulation and the number of trials in which the adjuvant is utilized in a repeat vaccine formulation.