TABLE 1.
Characteristics of the HVR5 substitutions
| Virus | Upstream HVR5 se-quence | Upstream linker | Inserted peptide | Down-stream linker | Downstream HVR5 se-quence |
|---|---|---|---|---|---|
| AdIE30 | FFS | NTTSLNDRQGNATK | PKVVLYS | ||
| AdIE32 | FFS | STTINI | PKVVLYS | ||
| AdIE33 | FFS | TPGANPPAGGSGNEEYK | PKVVLYS | ||
| AdIE31 | FFS | NLDSLEQPTTRAQKPRLD | LYS | ||
| AdIE35 | FFS | DNAPASTTNKDK | L | PKVVLYS | |
| AdIE37 | FFS | G | DNAPASTTNKDK | PKVVLYS | |
| AdIE39 | FFS | GS | DNAPASTTNKDK | PKVVLYS | |
| AdIE40 | FFS | S | DNAPASTTNKDK | PKVVLYS | |
| AdIE43 | FFS | G | DNAPASTTNKDK | LGG | PKVVLYS |
| AdIE44 | FFS | G | DNAPASTTNKDK | LGS | PKVVLYS |
| AdIE45 | FFS | G | DNAPASTTNKDK | LS | PKVVLYS |
| AdIE46 | FFS | G | DNAPASTTNKDK | LSG | PKVVLYS |
| AdIE47 | FFS | G | DNAPASTTNKDK | LSS | PKVVLYS |
| AE57 | FFS | GS | DCRGDCF | GS | PKVVLYS |