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. 2024 Jul 3;9(28):30945–30953. doi: 10.1021/acsomega.4c03949

Figure 2.

Figure 2

Cytotoxic effect of targeted AAV-iCasp9 and exo-AAV6-iCasp9 vectors in vitro. The viability of Huh7 cells 72 h after transduction was determined using an ATP assay. Data are represented in comparison to mock-treated cells. Cell viability graph for (A) AAV-iCasp9 vectors and (B) exo-AAV6-iCasp9 vectors. Cell control: mock-treated; positive control: 0.1% Triton X-100. Data are presented as mean ± SD (for each condition, n = 3 replicates, **p ≤ 0.01, ***p ≤ 0.001 in comparison to cell control, #p ≤ 0.05 in comparison to AAV6-CAG-iCasp9 or Exo-AAV6-CAG-iCasp9).