Table 2.
Blood serum low abundant proteins differentially enriched in strong recoverers (SR) or non-recoverers (NR)
| Gene name | Protein name | log2FC (NR vs. SR) |
SR enrichement (folds) |
NR enrichment (folds) |
p-value | FDR | ELISA | |
|---|---|---|---|---|---|---|---|---|
| CALU | Calumenin | -1.047 | 2.07 | 2.6E-05 | 0.037 | ✓* | ||
| SERPINE1 | Serpin family E member 1 | -1.144 | 2.21 | 2.8E-05 | 0.037 | ✓ | ||
| CTSW | Cathepsin W | -0.735 | 1.66 | 1.6E-04 | 0.068 | |||
| RAP1B/RAP1A | Ras-related protein Rap-1B | -0.700 | 1.62 | 2.3E-04 | 0.068 | |||
| ANGPT1 | Angiopoietin-1 | -0.748 | 1.68 | 2.4E-04 | 0.068 | ✓ | ||
| ARHGAP35 | Rho GTPase activating protein 35 | -1.587 | 3 | 6.8E-04 | 0.091 | ✓ | ||
| FKBP4 | FKBP prolyl isomerase 4 | -0.945 | 1.92 | 7.4E-04 | 0.091 | |||
| FHOD1 | FH1/FH2 domain-containing protein 1 | -0.794 | 1.73 | 7.5E-04 | 0.091 | |||
| B4GALT7 | Beta-1.4-galactosyltransferase 7 | -0.979 | 1.97 | 8.7E-04 | 0.094 | |||
| CNDP1 | Beta-Ala-His dipeptidase | -0.713 | 1.64 | 9.9E-04 | 0.094 | |||
| PIN1 | PDZ domain containing 2 | -1.158 | 2.23 | 1.2E-03 | 0.094 | ✓ | ||
| TCN2 | Transcobalamin-2 | -0.700 | 1.62 | 1.6E-03 | 0.096 | ✓ | ||
| AGER | Advanced glycosylation end product-specific receptor | 0.968 | 1.96 | 5.4E-05 | 0.048 | ✓ | ||
| DEFA1/DEFA3 | Defensin alpha 1 / Defensin alpha 3 | 1.147 | 2.21 | 4.1E-04 | 0.078 | ✓ | ||
| ITPA | Inosine triphosphate pyrophosphatase | 0.826 | 1.77 | 6.5E-04 | 0.091 | |||
| BPIFB2 | BPI fold containing family B member 2 | 1.419 | 2.67 | 1.0E-03 | 0.094 | |||
| UPB1 | Beta-ureidopropionase | 0.806 | 1.75 | 1.2E-03 | 0.094 | |||
| ADM | Pro-adrenomedullin | 0.689 | 1.61 | 1.3E-03 | 0.094 | |||
| RACK1 | Small ribosomal subunit protein RACK1[…] | 1.067 | 2.09 | 1.4E-03 | 0.095 | ✓* | ||
| STXBP5 | Syntaxin binding protein 5 | 0.897 | 1.86 | 1.4E-03 | 0.095 | |||
| LSM1 | LSM1 homolog. mRNA degradation associated | 0.922 | 1.89 | 1.5E-03 | 0.095 | |||
| OLR1 | Oxidized low-density lipoprotein receptor 1 | 1.125 | 2.18 | 1.7E-03 | 0.096 | ✓* | ||
| CTSG | Cathepsin G | 0.973 | 1.96 | 1.7E-03 | 0.096 | ✓ | ||
| CD300A | CMRF35-like molecule 8 | 0.900 | 1.86 | 1.7E-03 | 0.096 | ✓ | ||
✓ Selected for ELISA validation; * Current available kits not sensitive enough for a reliable evaluation of the protein in our samples