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. 2024 Jul 17;22:666. doi: 10.1186/s12967-024-05344-y

Table 3.

Serum levels of proteins confirmed by ELISA to be related to neurological recovery of patients (no recovery (NR) vs. strong recovery (SR)), compared with those in healthy controls (HC) and patients with spine fracture without neurological damage (SPFC).

HC SPFC SCI NR SCI SR
TCN2 (pg/ml) 532 ± 27 525 ± 65 921 ± 158 ** ^ 627 ± 109
ARHGAP35 (ng/ml) 25.2 ± 3.1 29.1 ± 7.1 22 ± 3.7 41.3 ± 10.4
CD300a (ng/ml) 1.27 ± 0.18 1.66 ± 0.65 14.93 ± 8.89 ** ^ 3.13 ± 1.17 *
SERPINE1 (ng/ml) 13.6 ± 0.6 14.3 ± 1.4 21.2 ± 1.7 *** ^ 25.7 ± 2.6 *** ^^^
DEFA1 (ng/ml) 934 ± 64 1238 ± 273 2797 ± 503 *** ^^ 1602 ± 319 **

Mann-Whitney’s test significance: * p < 0.05 vs. HC; ** p < 0.01 vs. HC; *** p < 0.001 vs. HC; ^ p < 0.05 vs. Spine Fracture; ^^ p < 0.01 vs. Spine Fracture; ^^^ p < 0.001 vs. Spine Fracture

HC: healthy controls; SPFC: patients with spine fracture without neurological damage; NR: SCI patients with no recovery; SR: SCI patients with strong recovery