Table 3.
Agreement between 15 HPV genotypesa detected by both LiPA-25 and other 7 assays.
| Type | Bohui-24 (%) | Yaneng-23 (%) | Tellgen-27 (%) | Hybribio-16 (%) | Hybribio-23 (%) | Bioperfectus-21 (%) | Sansure-26 (%) |
|---|---|---|---|---|---|---|---|
| Swab | n = 1,725 | n = 1,719 | n = 1,697 | n = 1,710 | n = 1,715 | n = 1,726 | n = 1,726 |
| Concordant | 1,401 (81.2) | 1,432 (83.3) | 1,349 (79.5) | 1,434 (83.9) | 1,438 (83.8) | 1,376 (79.7) | 1,334 (77.3) |
| Both negative | 700 (40.6) | 695 (40.4) | 677 (39.9) | 692 (40.5) | 682 (39.7) | 658 (38.1) | 609 (35.3) |
| Single types | 489 (28.3) | 530 (30.8) | 474 (27.9) | 522 (30.5) | 533 (31.1) | 496 (28.7) | 498 (28.9) |
| Multiple types | 212 (12.3) | 207 (12.1) | 198 (11.7) | 220 (12.9) | 223 (13.0) | 222 (12.9) | 227 (13.1) |
| Compatible | 147 (8.5) | 162 (9.4) | 144 (8.5) | 146 (8.5) | 176 (10.3) | 220 (12.8) | 241 (14.0) |
| LiPA-25 additional types | 70 (4.1) | 87 (5.1) | 64 (3.8) | 78 (4.5) | 59 (3.4) | 36 (2.1) | 28 (1.6) |
| Otherb additional types | 71 (4.1) | 71 (4.1) | 72 (4.2) | 61 (3.6) | 109 (6.4) | 179 (10.4) | 208 (12.1) |
| Both additional types | 6 (0.3) | 4 (0.2) | 8 (0.5) | 7 (0.4) | 8 (0.5) | 5 (0.3) | 5 (0.3) |
| Discordant | 177 (10.3) | 125 (7.3) | 204 (12.0) | 130 (7.6) | 101 (5.9) | 130 (7.5) | 151 (8.7) |
| LiPA-25 additional types | 147 (8.5) | 95 (5.5) | 169 (10.0) | 107 (6.2) | 66 (3.9) | 53 (3.0) | 31 (1.8) |
| Otherb additional types | 24 (1.4) | 26 (1.5) | 29 (1.7) | 20 (1.2) | 33 (1.9) | 67 (3.9) | 116 (6.7) |
| Both additional types | 6 (0.4) | 4 (0.3) | 6 (0.3) | 3 (0.2) | 2 (0.1) | 10 (0.6) | 4 (0.2) |
| Biopsy | n = 56 | n = 56 | n = 56 | n = 56 | n = 56 | n = 56 | n = 56 |
| Concordant | 53 (94.6) | 52 (92.8) | 54 (96.4) | 50 (89.3) | 48 (85.7) | 52 (92.8) | 45 (80.4) |
| Both negative | 3 (5.4) | 3 (5.4) | 3 (5.4) | 2 (3.6) | 2 (3.6) | 3 (5.4) | 2 (3.6) |
| Single types | 50 (89.2) | 49 (87.4) | 51 (91.0) | 48 (85.7) | 46 (82.1) | 49 (87.4) | 43 (76.8) |
| Multiple types | 0 (0.0) | 0 (0.0) | 0 (0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| Compatible | 0 (0.0) | 3 (5.4) | 2 (3.6) | 4 (7.1) | 6 (10.7) | 3 (5.4) | 9 (16.0) |
| LiPA-25 additional types | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| Otherb additional types | 0 (0.0) | 3 (5.4) | 2 (3.6) | 4 (7.1) | 6 (10.7) | 3 (5.4) | 9 (16.0) |
| Both additional types | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0) | 0 (0.0) |
| Discordant | 3 (5.4) | 1 (1.8) | 0 (0.0) | 2 (3.6) | 2 (3.6) | 1 (1.8) | 2 (3.6) |
| LiPA-25 additional types | 3 (5.4) | 1 (1.8) | 0 (0.0) | 1 (1.8) | 1 (1.8) | 1 (1.8) | 0 (0.0) |
| Otherb additional types | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (1.8) | 1 (1.8) | 0 (0.0) | 1 (1.8) |
| Both additional types | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (1.8) |
a
HPV types 6, 11, 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 66.
b
Other indicated HPV only detected by Sansure-26, Bioperfectus-21, Bohui-24, Yaneng-23, Tellgen-27, Hybribio-23, and Hybribio-16, respectively.
Abbreviation: HPV, human papillomavirus.