FIG. 4.
Time course of HSV-1 infection in 129/Sv//Ev, GKO, and RGKO mice. The right eyes of 6- to 8-week-old male mice were inoculated with 106 PFU of HSV-1 by ocular scarification. Three mice from each group were sacrificed daily from day 2 through day 7, and HSV-1 titers in brain stem cells were determined. The whole-tissue HSV-1 titers were plotted against day postinoculation for 129/Sv//Ev (strain T), GKO (strain G), and RGKO (strain R) mice. There was no statistically significant difference in HSV-1 titers in the brain stem cells for the three groups of mice.