TABLE 1.
Neonates |
Infants |
|||||
---|---|---|---|---|---|---|
Variable | Group I (UVH) |
Group II (TGA) |
P value* | Group III (LRS) |
Group IV (TOF) |
P value* |
Patients | 24 | 11 | 55 | 25 | ||
Age | 9 ± 8 d | 10 ± 9 d | .87 | 10 ± 2 mo | 4 ± 3 mo | .02 |
Weight (kg) | 3.3 ± 0.4 | 3.5 ± 0.4 | .26 | 6.4 ± 1.4 | 5.2 ± 1.5 | .09 |
Males (n) | 10 (42%) | 10 (91%) | <.01 | 28 (50%) | 16 (64%) | .28 |
Surgery type | Norwood† | Arterial switch | Primary repair | Primary repair | ||
Cardiac lesion | 15 HLHS; 3 Shone’s complex; 2 IAA, HAA; 2 DORV, HRV, HAA; 2 tricuspid atresia, TGA, HRV, HAA | 11 d-TGA | 40 VSD 15 AVSD | 25 TOF | ||
Preoperative data | ||||||
HR (min−1) | 151 ± 16 | 147 ± 25 | .6 | 134 ± 20 | 135 ± 18 | .8 |
MAP (mm Hg) | 49 ± 7 | 48 ± 5 | .6 | 62 ± 12 | 61 ± 15 | .7 |
Pulse oximetry (% saturation) | 91 ± 6 | 89 ± 6 | .3 | 98 ± 0.4 | 94 ± 1 | <.01 |
Mechanical ventilation | 16 (67%) | 10 (91%) | .4 | 4 (7%) | 4 (30%) | .4 |
PGE1 | 21 (88%) | 11 (100%) | .5 | 0 (0%) | 1 (4%) | .4 |
BUN (mg/dL) | 15 ± 8 | 10 ± 6 | .2 | 11 ± 5 | 8 ± 5 | .04 |
Blood creatinine (mg/dL) | 0.5 ± 0.2 | 0.6 ± 0.1 | .2 | 0.4 ± 0.1 | 0.4 ± 0.1 | .2 |
Data presented as mean ± SD or number (%). UVH, Univentricular heart; TGA, d-transposition of great arteries; LRS, left to right shunt; TOF, tetralogy of Fallot; HLHS, hypoplastic left heart syndrome; IAA, interruption of aorta; HAA, hypoplastic aortic arch; DORV, double outlet right ventricle; HRV, hypoplastic right ventricle; VSD, ventricular septal defect; AVSD, atrioventricular septal defect; HR, heart rate; MAP, mean arterial pressure; PGE1, prostaglandin E1; BUN, blood urea nitrogen.
P values for comparisons between groups I and II (neonates) and between groups III and IV (infants).
Of 24 patients, 22 underwent right ventricle-pulmonary artery conduit, 1 modified Blalock-Taussig shunt, and 1 an aortopulmonary shunt.