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. 2024 Mar 28;14(4):213–224. doi: 10.4103/mgr.MEDGASRES-D-23-00036

Figure 8.

Figure 8

O3-RI prevents SD-induced upregulation of NLRP3 and IL-1β in hippocampus and colon.

Note: (A) Western blotting results. (B–E) Quantitative analysis of NLRP3 and IL-1β expression in hippocampus and colon, which was normalized by control group. Data are expressed as mean ± SD (n = 5). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 (one-way analysis of variance, followed by the Tukey's multiple comparison test). Ctrl: Control; IL: interleukin; ns: no significance; O3-RI: ozone rectal insufflation; O3-RI-H: high-concentration O3-RI; O3-RI-L: low-concentration O3-RI; SD: sleep deprivation.