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. 2024 Apr 1;19(2):217–227. doi: 10.4103/RPS.RPS_52_23

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Fig. 6 — Effects of ethanolic extract of JE on histopathological changes of BDL-induced cholestasis (hematoxylin and eosin staining) in rats. SC group view: relatively normal hepatic lobule and portal triad structure. BDL group view: severe BD proliferation (BDL1, black arrow, 200×), moderate portal inflammation (BDL2, circle/arrow, 400×), mild/moderate piecemeal necrosis (BDL3, circle, 400×), and fibrosis of some portal tract (BDL4, arrow, 200×). JE group view: relatively normal hepatic lobule and portal triad structure (SC + JE, 200×). BDL + JE group view: severe BD proliferation (BDL + JE1, arrow, 200×), severe BD proliferation associated with moderate portal inflammation (BDL + JE2, blue/black arrows and circle, 400×), focal inflammation (BDL + JE3, blue arrow) with hepatocyte necrosis (BDL + JE3, black arrow/circle. 400×) and mild piecemeal necrosis portal tract (BDL + JE4, arrow/circle, 400×). SC, Sham control; PV, portal vein; BD, bile duct; CV, central vein; BDL, bile duct ligation; JE, Juniperus excels.