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Comparison of proteome profile of TCR-activated PBMC from adolescent IBD patients demonstrate a significant decrease in phosphorylation at known activation sites for Hck, Fyn, FAK, ERK1/2, STAT5a, p53 and β-catenin with a significant increase in activation-associated phosphorylation seen at HSP27 only. Results represent mean±SEM for N = 8 age and gender-matched patients per group. *P<0.05, **P<0.01, ***P<0.001.
