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. 2024 Jul 5;15:1369478. doi: 10.3389/fmicb.2024.1369478

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Copyright © 2024 Guan, Zhao, Li, Zhang, Guo, Luo, Jiang, Li, Liu, Chen, Zhao and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Alterations in gut microbiota affected by drugs. (A) α-diversity (Shannon index) of ACS patients treated by different drugs at three stages of therapy. (B) Principal Coordinates Analysis (PCoA) of patients used different medications at three stages of therapy (Bray–Curtis distance). (C) Microbiota that changed significantly after treatment with rosuvastatin. (D) Microbiota that changed significantly after treatment with atorvastatin (*adjust p < 0.05, **adjust p < 0.01, and ***adjust p < 0.001, Kruskal–Wallis test, Benjamini–Hochberg FDR).