Fig. 5.

Co-stimulatory molecules by RNA-seq and qPCR at Week 24 in patients with more active than stable and patients with more stable than active lesions (Cohort 2). lgFCH, log fold change. Red symbols: ⁺P < 0.1 vs. baseline; *P < 0.05 vs. baseline; **P < 0.01 vs. baseline; ***P < 0.001 vs. baseline. Black symbols: ⁺P < 0.1 vs. placebo; *P < 0.05 vs. placebo; **P < 0.01 vs. placebo