TABLE 1.
Donor | Cell line | Phenotypeb | % Specific lysisc with:
|
|||
---|---|---|---|---|---|---|
vac-G1 | vac-G2 | vac-N | vac | |||
A | 1-C8 | CD8 | −2.2 | —d | 70.3 | 5.5 |
3-G7 | CD8 | −2.6 | — | 55 | −1.9 | |
10-E2 | CD8 | −0.5 | — | 53.1 | 0.9 | |
10-B5 | CD8 | −1.6 | 3.2 | 58.8 | — | |
1-G5 | CD4 | −0.4 | — | 66.7 | 1.6 | |
1-D6 | CD4 | −3.4 | — | 61.4 | −0.7 | |
B | 3-E3 | CD4 | 33.5 | −0.3 | −0.4 | −0.1 |
10-C11 | CD4 | 30.9 | −2.6 | −2.8 | −2.9 | |
10-F4 | CD4 | 25.4 | −2.4 | −1.0 | −0.9 | |
C | 1A-B7 | CD8 | −2.9 | −7.0 | 87.7 | — |
3A-B8 | CD8 | −6.3 | −7.0 | 60.0 | — | |
3A-C4 | CD8 | −6.1 | 1.0 | 44.5 | — | |
3A-C10 | CD8 | −6.1 | −7.2 | 68.5 | — | |
3A-G3 | CD8 | 0.0 | −0.2 | 84.1 | — | |
3A-F2 | CD4 | 0.3 | 2.8 | 47.0 | — | |
3-E10 | CD4 | −4.6 | — | 40.3 | — | |
3-F8 | CD4 | −3.6 | — | 55.6 | — |
Data from representative cell lines are shown. E/T ratios vary from 20:1 to 50:1.
Cell lines were >95% CD4 or CD8 by flow cytometry.
Boldface indicates significant target cell recognition.
—, Target not tested.