TABLE 4.
Cohorts | Models | AUC (95% CI) | Sensitivity | Specificity | PPV | NPV | Accuracy |
---|---|---|---|---|---|---|---|
Training cohort | Nomogram | 0.908 (0.839–0.954) | 0.727 | 0.855 | 0.762 | 0.831 | 0.805 |
PPF radiomics signature | 0.835 (0.754–0.898) | 0.704 | 0.797 | 0.689 | 0.809 | 0.761 | |
Intratumoral radiomics signature | 0.822 (0.739–0.888) | 0.591 | 0.841 | 0.703 | 0.763 | 0.743 | |
Validation cohort | Nomogram | 0.886 (0.763–0.959) | 0.737 | 0.867 | 0.778 | 0.838 | 0.816 |
PPF radiomics signature | 0.833 (0.699–0.924) | 0.684 | 0.833 | 0.722 | 0.806 | 0.775 | |
Intratumoral radiomics signature | 0.751 (0.607–0.863) | 0.526 | 0.900 | 0.769 | 0.750 | 0.755 |
Abbreviations: AUC, area under the receiver operating characteristic curve; CI, confidence interval; NPV, negative predictive value; PPF, periprostatic fat; PPV, positive predictive value.