Table 4.
Neonatal outcome
| Characteristic | Study group – positive aPL (n=20) | Control group – negative aPL (n=35) | P value |
|---|---|---|---|
| Small for gestational age a | 5 (25%) | 6 (17.1%) | 0.7 |
| Apgar score ≤ 7 at 5-minute | 3 (15%) | 3 (8.6%) | 0.7 |
| Length of NICU hospitalization (days) | 34 (16.8-57.8) | 30 (19.5-76.5) | 0.9 |
| Respiratory distress syndrome (RDS) | 10 (50%) | 13 (37.1%) | 0.5 |
| Intra-ventricular hemorrhage (IVH) | 2 (10%) | 5 (14.3%) | 0.7 |
| IVH 3+4 | 0 | 1 (2.9%) | 1 |
| periventricular leukomalacia (PVL) | 0 | 0 | 1 |
| Necrotizing enterocolitis (NEC) | 1 (5%) | 2 (5.7%) | 1 |
| Sepsis | 4 (20%) | 2 (5.7%) | 0.06 |
| Seizures | 0 | 1 (2.9%) | 1 |
| Hypoglycemia | 1 (5%) | 4 (11.4%) | 0.6 |
| Hyperbilirubinemia | 12 (60%) | 21 (60 %) | 1 |
| CPAP or mechanical ventilation | 7 (35%) | 12 (34.3%) | 1 |
| Retinopathy of prematurity (ROP) | 6 (30%) | 2 (5.7%) | 0.02 |
| Broncho-pulmonary disease (BPD) | 1 (5%) | 3 (8.6%) | 1 |
| Perinatal death | 3 (15%) | 1 (2.9%) | 0.1 |
Data are presented as median (interquartile range) or means (standard deviation) for continuous variables, or as number (percent) for categorical variables.
NICU – Neonatal intensive care unit; CPAP - continuous positive airway press
Small for gestational age defined as birthweight percentile below the 10th percentile for the gestational age based on customized nomograms.