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. 2024 Jun 17;5(1):zpae039. doi: 10.1093/sleepadvances/zpae039

Table 3.

Within-Person Mediated Effects of Pain Intensity and Mood on Sleep and Opioid Use

Predictors Mediators a path (se) b path (se) c path (se) Indirect effect (se) 95% confidence interval
Lower Upper
Sleep quality Pain intensity −0.16 (0.04)* 0.30 (0.04)* −0.002 (0.03) −0.05 (0.01)* −0.08 −0.02
WASO 0.006 (0.002)* 0.298 (0.039)* 0.001 (0.001) 0.002 (0.001)* 0.001 0.003
SOL 0.007 (0.001)* 0.299 (0.026)* 0.001 (0.001) 0.002 (0.001)* 0.001 0.003
TST −0.001 (0.0001) 0.292 (0.026)* 0.0001 (0.0001) 0.0001 (0.0001) −0.0001 0.0001
Sleep quality Mood 0.05 (0.04) −0.01 (0.02) 0.0001 (0.001) −0.002 0.002
WASO −0.002 (0.001) −0.006 (0.20) 0.0001 (0.0001) −0.001 0.001
SOL −0.001 (0.001) −0.009 (0.019) 0.0001 (0.001) −0.0001 0.0001
TST 0.001 (0.001) −0.003 (0.019) 0.0001 (0.0001) −0.0001 0.0001

WASO, wake after sleep onset; SOL, sleep onset latency; TST, total sleep time. c path represents the total effect from sleep variables to opioid use, and is the same for both mediators and only reported once. * indicates statistically significant regression pathway.