Table 1 |.
Relevance of cytokines to endometrial function
| Protein | Relevance | References |
|---|---|---|
| Activin A | Expressed in decidualized stromal cells | 45,46 |
| Amphiregulin | Role in receptivity and blastocyst attachment | 43 |
| Angiogenin | Angiogenesis; Decidualization | 72 |
| Angiopoetin-1 | Maintains vessel integrity and vascular remodeling | 5,39 |
| Endoglin | Endometrial receptivity | 73 |
| Endostatin/Collagen XVIII | Maturation and stabilization of vessels | 41 |
| Endothelin-1 | Vasoconstriction; Myometrial contraction | 6,74 |
| FGF-1 | Angiogenesis | 39,40 |
| IGFBP-2 | Found in stroma; Abundant in secretory phase | 75,76 |
| PDGF | Angiogenesis; Stromal cell motility and proliferation | 42 |
| Pentraxin 3 | Angiogenesis; Matrix Remodeling; Inflammation; Decidualization | 77 |
| Platelet Factor 4 | Repair following menses | 44 |
| Prolactin | Decidualization | 78 |
| Serpin F1 | Regulation of angiogenesis | 79 |