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. 2024 Jun 19;16(6):e62706. doi: 10.7759/cureus.62706

Table 2. Unifactorial analysis of demographic and clinical characteristics in relation to FAK positivity and IRS score.

All categorical variables were presented as frequencies (%). FAK: focal adhesion kinase, IRS: immunoreactive score.

Variables FAK positivity p-value FAK IRS score p-value
Negative (n=40) Positive (n=50) No (n=51) Weak-moderate (n=39)
Age; mean ± SD 60.03 ± 11.96 59.90 ± 13.83 0.964 60.18 ± 12.03 59.67 ± 14.24 0.854
Histologic type Clear cell 33 (56.9) 25 (43.1) <0.005 40 (69.0) 18 (31.0) <0.005
Papillary 2 (13.3) 13 (86.7) 4 (26.7) 11 (73.3)
Chromophobe 2 (18.2) 9 (81.8) 4 (36.4) 7 (63.6)
Grade 1 6 (66.7) 3 (33.3) 0.234 6 (66.7) 3 (33.3) 0.074
2 21 (46.7) 24 (53.3) 30 (66.7) 15 (33.3)
3 and 4 13 (36.1) 23 (63.9) 15 (41.7) 21 (58.3)
Gender Male 29 (46) 34 (54) 0.817 13 (48.1) 14 (51.9) 0.355
Female 11 (40.7) 16 (59.3) 38 (60.3) 25 (39.7)
Stage Τ 1 28 (44.4) 35 (55.6) 0.996 36 (57.1) 27 (42.9) 0.774
2 5 (45.5) 6 (54.5) 7 (63.6) 4 (36.4)
3 7 (43.8) 9 (56.3) 8 (50) 8 (50)