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. 2015 Jan 13;2015(1):CD005397. doi: 10.1002/14651858.CD005397.pub4

1. Unilateral peripheral vestibulopathies.

Vestibulopathy Incidence Aetiology Symptoms Diagnosis Treatment
Benign paroxysmal positional vertigo (BPPV) (idiopathic)
 
 (Cabrera Kang 2013; Hilton 2014) All age groups
Peak 40 to 60 years
11 to 64 per 100,000 pa
 
 Females > males
Various:
Canalithiasis (free‐floating debris in semicircular canals)
Cupulolithiasis (debris attached to cupula)
Episodic vertigo after rapid head motion, lasting seconds to 1 minute; +/‐ nausea; some balance deficits; nystagmus (latency, fatigue, rotatory and beating) Dix‐Hallpike test (post) (Dix 1952)
Lateral head‐trunk tilt (Brandt 1999) etc.
Use of ENG to record nystagmus
1. Repositioning manoeuvre/s relative to semicircular canal (Cabrera Kang 2013; Epley 1992; Semont 1988)
2. VR
3. Vestibular suppressant medication for symptom relief
4. Vestibular neurectomy or post‐semicircular canal obliteration
Vestibular neuritis (Gans 2002)/neuronitis and labyrinthitis (Strupp 1998) Unknown Unclear
Viral, autoimmune or vascular mechanisms
Viral or bacterial infection of labyrinthine fluids (labyrinthitis) or CN VIII (neuritis)
Acute onset
Distressing tonal imbalance producing: rotatory vertigo; spontaneous nystagmus (horizontal); falls to the affected side; nausea
From history and presentation
ENG and caloric irrigation show reduced or no response in horizontal semicircular canal; ocular tilt reaction
Symptomatic medication (vestibular suppressants)
Bacterial/viral management
VR
Ménière's disease
 (Scott 1994; Strupp 2013) Unknown
Equal males and females
Greatest in 3rd and 4th decades
Unclear
Endolymphatic hydrops
Acute: unpredictable and episodic
hearing loss, tinnitus and vertigo, +/‐ nausea, vomiting, visual disturbance, anxiety, motion sensitivity
Chronic: UPVD or bilateral PVD
History and presentation
Audiogram
ENG with calorics
Imaging the inner ear with high‐resolution MRI after tympanic gadolinium injection
Acute: medication (transtympanic glucocorticoids, antihistamines, suppressants)
 diet; low salt; diuretics
Chronic: VR, psychological support, surgery (see next row)
Postoperative:
 Labyrinthectomy
Neurectomy
Intra‐tympanic injection of gentamycin
Unknown For management of intractable UPVD, tumour removal, Ménière's UPVD, i.e. spontaneous nystagmus, vertigo, disequilibrium, VOR gain, postural instability VR
Symptomatic medication (Dowdal‐Osborn 2002)
Perilymphatic fistula (Baloh 2003) Unknown History of head trauma, barotraumas or sudden strain; may be associated with chronic otitis or cholesteatoma; perforation of tympanic membrane Unilateral hearing loss, vertigo, nystagmus Induce symptoms by pressure in external ear canal
Positive head thrust
ENG
Audiography
Symptomatic medication
Surgical packing

ENG: electronystagmography
 MRI: magnetic resonance imaging
 pa: per year
 UPVD: unilateral peripheral vestibular disorder
 VOR: vestibular ocular reflex
 VR: vestibular rehabilitation