Figure 3.

Electroacupuncture (EA) treatment alleviates PINK1/Parkin-mediated mitochondrial dysfunction in brain tissues of migraine rats. (a) Mitochondrial damage in brain tissues of rats was observed by transmission electron microscopy (scale bar = 1 μm). Red arrows indicate mitochondria. (b) Reactive oxygen species level in the mitochondria of rats was measured by flow cytometry. (c) The expression of PINK1 and Parkin was detected by Western blotting. A rat model of migraine was established by intraperitoneal injection with 10 mg/kg nitroglycerin and then treated by EA. **P < 0.01 versus control; ^#P < 0.05 and ^##P < 0.01 versus model + nonacupuncture point EA