Table 1.

Clinical profile of patients at the time of admission/at the onset of massive transfusion and after massive transfusion compared between retrospective controls (Group A) and thromboelastography-guided transfusion support group (Group B)

Normal values	Overall	At the time of admission			Postmassive transfusion
		Group A	Group B	P	Group A	Group B	P
Demographic details
Age, mean±SD		42.7±16.3	43.7±16.9	41.7±15.7	0.37
Male (%)		14565.3	7566.3	7064.2	0.42
Female (%)		7734.7	3833.6	3935.7
Hypotension (mmHg) (%)	SBP <90, DBP <60	11350.9	6456.6	4945	0.05
Tachycardia (beats/min) (%)	HR >100	10346.3	5548.7	4844	0.08
Hematologic parameters, mean±SD
Hemoglobin (g/dL)	13–17	9.04±2.7	9.05±2.7	9.03±2.9	0.57	9.07±1.8	9.98±2.5	0.007
Hematocrit (%)	40–50	27.5±9.3	27.1±8.1	27.8±10.4	0.29	26.2±5.4	29.3±8.05	0.003
Platelet count (/µL)	150000–450000	206235±127166	206281±121592	206188±133219	0.23	147000±122858	119865±63029	0.08
WBC (/µL)	4000–1000	16299±9194	16919±9209	15672±9184	0.92	13108±6230	14835±22087	0.54
Biochemistry parameter, mean±SD
pH	7.35–7.46	7.19±0.22	7.10±0.23	7.27±0.17	0.01	7.14±0.19	7.27±0.18	<0.001
Na+ (mmol/L)	136–146	137.1±7.3	136.2±7.9	138±6.6	0.06	136.6±7.4	137.5±12.8	0.58
K+ (mmol/L)	3.4–4.5	4.14±0.23	4.1±0.9	4.1±1	0.75	3.9±1	4.3±1.69	0.09
HCO3− (mmol/L)	23–29	16.47±5.2	15.6±5.7	17.2±4.6	0.05	17.41±7.4	17.41±5.2	0.99
Cl− (mmol/L)	98–106	103.7±6.8	103.7±8.7	103.7±5.1	0.98	105.9±9.5	102.4±13.6	0.10
Ca2+ (mmol/L)	2.2–2.7	0.9±0.1	0.8±0.1	1.0±0.1	0.72	0.86±0.2	1.09±0.50	0.10
Base excess (mmol/L)	−3–+3	−10.41±7.46	−11±8.31	−9.2±6.3	0.04	−9.4±7.4	−7.9±7.1	0.35
Coagulation parameters, mean±SD
PT (s)	9.6–12.5	22.7±24.8	23.6±25.9	22±24	0.55	14.7±7.2	15.07±6.29	0.82
aPTT (s)	26.8–33.2	45.3±30.9	45.5±30.7	45±31.1	0.94	38.2±22.6	35.9±18.7	0.56
Fibrinogen (mg/dL)	200–400	126±107.9	122.2±133.4	128.8±87.5	0.15	219±161.7	267.1±160.7	0.31

SD=Standard deviation, WBC=White blood cells, aPTT=Activated partial thromboplastin time, PT=Prothrombin time, DBP=Diastolic blood pressure, SBP=Systolic blood pressure