Table 10.

Antipyretic, antihypertensive and vasodilator effects of D. viscosa.

Activities	Part Used	Extracts	Experimental approach	Key results	References
Antipyretic effect	Leaves and flowers	Methanolic extracts and decoctions of D. viscosa	Brewer's yeast-induced pyrexia method	Important reduction of the rectal temperature of the rats after 4 h compared to control groups treated with leaves and flowers extracts at the doses of 600 and 800 mg/kg.	92
Antihypertensive and vasodilator effects	Leaves	Methanolic extract (40 mg/kg/day)	Non-invasive indirect tail-cuff plethysmographic method. In vitro vasorelaxant effect.	- The MeOH extract has been found to possess antihypertensive properties. When administered together with l-NAME, it prevented an increase in SBP, which remained steady at 115 ± 1 mmHg after a treatment period of four weeks. - In ex-vivo experiments, the MeOH extract induced relaxation in pre-contracted ring aortas (resulting in 54 ± 2% relaxation at a concentration of 3 g/L). However, when the rings were denuded, the MeOH extract was unable to relax the pre-contracted aortic rings.	96
		Aqueous extract (250 mg/kg/day)	Indirect tail-cuff plethysmographic method (TCP)	It demonstrated a substantial capacity to inhibit the progression of l-NAME-induced hypertension and exhibited a negative dose dependent inotropic effect in cardiac muscle.	95