Table 2.

Toxicological properties of D. viscosa.

Use parts	Extracts	Dose administration	Route of administration	Model	Effects	References
Aerial parts	Acetone extract	200 mg/kg to 1000 mg/kg for 60 days	Intraperitoneally	Toxicity	The doses investigated had no death and no toxic effect	60
Leaves and flowers	Methanolic extracts	400 and 800 mg/kg for over 14 days. 400 and 800 mg/kg for over 28 days	Orally	Acute toxicity Sub-chronic toxicity	None of the doses caused death. No signs of both acute and sub-chronic toxicity.	59
Leaves and flowers	- Methanolic extracts - Essential oils	−300, 600, 1000, 1500, 2000, 2500 mg/kg of methanolic extract. −0.3, 0.5, 1, 1.5, 2, 3 mL/kg of essential oils. For 14 days	Orogastric route	Acute toxicity	No death during the observation period and no change the behavior of animals.	58
Leaves	Petroleum ether Dichloromethane Methanol extract Aqueous extract	DL50: 626 mg/kg DL50: 1288 mg/kg DL50: 2958 mg/kg DL50: >8000 mg/kg	Intraperitoneally	Acute toxicity	No maternal mortality and all the dosages administered in this study were sublethal,	49