Table 9.
Part Used | Extracts | Experimental approach | Key results | References |
---|---|---|---|---|
Leaves | Hydro-ethanolic extract | Carrageenan-induced paw edema (500 mg/kg) | The D. viscosa extract had significantly inhibited the paw edema mice after 6 h at a dose of 500 mg/kg body weight in comparison to the other groups. | 91 |
Aqueous extract | - Carrageenan-induced paw inflammation - measured the expression of inducible iNOS, MyD88, TLR-4, TNF-α and nitric oxide (NO) release from LPS-stimulated J774A.1 macrophages |
- Decreased the production of NO - Dose-dependent in vivo and in vitro inhibition of the expression of iNOS - Moderate reduction in paw edema after 6 h of carrageenan |
94 | |
Lipid extract (LLE) | Elastase enzyme Inhibition Activity | I = 25% (1 mg/mL) I = 45% (5 mg/mL) I = 72% (10 mg/mL) I = 82% (0.2 mg/mL) Epigallocatechin Gallate |
90 | |
Aerial parts | Methanolic extracts at different concentrations | In-vitro anti-inflammatory activity inhibition of albumin denaturation | I = 18.16 % (1.2 mg/mL) I = 35.43 % (1.6 mg/mL) I = 44.44 % (2 mg/mL) |
78 |
Leaves and Flowers | Methanolic extracts. Decoctions of leaves and flowers. | Carrageenan-induced paw edema | Major reduction of the paw edema after 4 h. | 92 |