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. 2024 Mar 11;14(4):355–380. doi: 10.1016/j.jtcme.2024.03.012

Table 9.

Anti-inflammatory activity of D. viscosa.

Part Used Extracts Experimental approach Key results References
Leaves Hydro-ethanolic extract Carrageenan-induced paw edema (500 mg/kg) The D. viscosa extract had significantly inhibited the paw edema mice after 6 h at a dose of 500 mg/kg body weight in comparison to the other groups. 91
Aqueous extract - Carrageenan-induced paw inflammation
- measured the expression of inducible iNOS, MyD88, TLR-4, TNF-α and nitric oxide (NO) release from LPS-stimulated J774A.1 macrophages
- Decreased the production of NO
- Dose-dependent in vivo and in vitro inhibition of the expression of iNOS
- Moderate reduction in paw edema after 6 h of carrageenan
94
Lipid extract (LLE) Elastase enzyme Inhibition Activity I = 25% (1 mg/mL)
I = 45% (5 mg/mL)
I = 72% (10 mg/mL)
I = 82% (0.2 mg/mL) Epigallocatechin Gallate
90
Aerial parts Methanolic extracts at different concentrations In-vitro anti-inflammatory activity inhibition of albumin denaturation I = 18.16 % (1.2 mg/mL)
I = 35.43 % (1.6 mg/mL)
I = 44.44 % (2 mg/mL)
78
Leaves and Flowers Methanolic extracts. Decoctions of leaves and flowers. Carrageenan-induced paw edema Major reduction of the paw edema after 4 h. 92