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. 2024 Jan 8;14(4):435–445. doi: 10.1016/j.jtcme.2024.01.003

Fig. 4.

Fig. 4

Photomicrographs of TH + neurons in the SNc of (A) Control group; (B) 6-OHDA group, (C) DTTS 10, (D) DTTS 30 and (E) DTTS 100 groups. F: quantitative results of the TH + neurons in the SNc as a percentage of the contralateral side, at 400× magnification. Photomicrographs of TH + relative optical density (ROD) in the striatum of (G) Control group; (H) 6-OHDA group, (I) DTTS 10, (J) DTTS 30 and (K) DTTS 100 groups. In L: quantitative results of the ROD in the striatum as a percentage of the contralateral side, at 400× magnification. Columns represent the mean e and bars indicate the SEM. Control: group of animals microinjected with vehicle and that received distillated water; 6-OHDA: group of animals microinjected with 6-hydroxydopamine and that received distillated water; DTTS 10, DTTS 30 and DTTS 100: group of animals microinjected with 6-hydroxydopamine and that received aqueous extract of Tradescantia spathacea at 10, 30 and 100 mg/kg, respectively. * indicates significant difference from Control group (****p < 0.0001), # indicates significant difference from 6-OHDA (###p < 0.001 and ####p < 0.0001) and + indicates difference from other doses of DTTS (++++ p < 0.0001). One-way analysis of variance with Bonferroni's post-tests.