FIGURE 3.

Radial dysplasia connective tissue cell‐derived extracellular matrix is significantly disorganised. Connective tissue cell‐derived extracellular matrix synthesised from control (a, b) and radial dysplasia (RD) (c, d) patient cells are stained with type I collagen and fibronectin. Box and whisker plot of order parameter values demonstrating RD cell line derived matrix (n = 6 different RD patient‐derived cell lines) is significantly more disorganised compared with the control cell line derived matrix (n = 4 different control cell lines) when stained for type I collagen (e) and fibronectin (f) fibres. Control, blue. RD, red.