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Illustrates the comparison of tumor microenvironment (TME) characteristics in patients with high-grade serous ovarian carcinoma before and after neoadjuvant chemotherapy (NACT). Pre-NACT H&E images show lower TIL density and less disorder in collagen fiber orientations, whereas post-NACT H&E images demonstrate higher TIL density and higher disorder in collagen fiber orientations. TME, Tumor Microenvironment; TIL, Tumor-Infiltrating Lymphocytes.
