Skip to main content
. 2024 Jul 20;5(8):e656. doi: 10.1002/mco2.656

TABLE 2.

Alterations in human gut microbiota composition in neurological disorders.

Disease Species Increased taxa Reduced taxa References
ASD Children with ASD

Phylum:

Proteobacteria

Genus:

Clostridium, Enterococcus,

Prevotella,

Alistipes

Species:

Roseburia inulivorans,

Roseburia sp.

Phylum:

Firmicutes

Genus:

Faecalibacterium,

Bifidobacterium

Species:

Roseburia intestinalis,

Roseburia faecis,

147

This is a review.
ASD Patients with ASD (y = 2–18)

Phylum:

Proteobacteria,

Fusobacteria,

Verrucomicrobia

Genes:

Lactobacillus,

Bacteroides,

Desulfovibrio,

Akkermansia

Genus:

Bifidobacterium,

Blautia,

Dialister,

Prevotella,

Turicibacter,

Veillonella,

Akkermansia muciniphila

139

This is a systematic review.
ASD Chinese children with ASD (y = 2–7, n = 48)

Genus:

Bacteroides,

Prevotella, Lachnospiracea_incertae_sedis, Megamonas

Species:

Bacteroides coprocola,

Bacteroides vulgatus,

Eubacterium eligens,

Prevotella copri,

Roseburia faecis

Phylum:

Proteobacteria, Verrucomicrobia

Genus:

Clostridium,

Escherichia/Shigella

Species:

Akkermansia muciniphila,

Dialister invisus,

Escherichia coli,

Bacteroides fragilis,

Haemophilus parainfluenzae,

Flavonifractor plautii

 148
ADHD Chinese children and adolescents (y = 6–15, n = 98)

Family:

Listeriaceae,

Prevotellaceae,

Veillonellaceae

Species:

Prevotella copri,

Prevotella buccae,

Bifidobacterium breve,

Bifidobacterium bifidum

Species:

Bacteroides ovatus,

Bacteroides nordii,

Bacteroides thetaiotaomicron,

Bacteroides intestinalis,

Bacteroides cellulosilyticus,

Bacteroides fluxus

 149
ADHD Children with ADHD (y = 6–16, n = 41)

Genus:

Desulfovibrio,

Roseburia,

Ruminococcaceae,

Agathobacter, Anaerostipes, Lachnospiraceae UCG‐010

Genus:

Bacteroides,

Prevotella

 150
ADHD Children with ADHD (mean age: 8.4, n = 30)

Genus:

Sutterella

Fusobacterium,

Alistipes,

Species:

Sutterella stercoricanis,

Bacteroides uniformis,

Bacteroides ovatus

Genus:

Prevotella,

Species:

Bacteroides coprocola

 151
AD Chinese patients with AD (y = 50–85, AD, n = 33; aMCI, n = 32)

Phylum:

Proteobacteria

Class:

Gammaproteobacteria

Family:

Veillonellaceae,

Enterobacteriaceae

Phylum:

Firmicutes,

Bacteroidetes

Family:

Clostridiaceae,

Lachnospiraceae,

Ruminococcaceae,

Blautia

 152
AD American patients with AD (mean age = 71.3, n = 25)

Phylum:

Bacteroidetes,

Proteobacteria

Family:

Gemellaceae,

Bacteroidaceae,

Rikenellaceae

Genus:

Blautia,

Phascolarctobacterium,

Gemella,

Bacteroides,

Alistipes,

Bilophila

Phylum:

Firmicutes,

Actinobacteria

Family:

Bifidobacteriaceae,

Ruminococcaceae,

Turicibacteraceae,

Clostridiaceae,

Mogibacteriaceae

Genus:

Clostridiaceae SMB53,

Dialister,

Clostridium,

Turicibacter,

Erysipelotrichaceae cc115,

Bifidobacterium,

Adlercreutzia

 153
AD Patients with AD (AD: mean age = 66.3, n = 30; MCI: mean age = 65.4, n = 30)

Phylum:

Firmicutes

Genus:

Lactobacillus,

Akkermansia,

Dorea,

Bifidobacterium,

Streptococcus,

Acinetobacter,

Blautia,

Escherichia

Phylum:

Bacteroidetes

Genus:

Parabacteroides,

Alistipes,

Bacteroides,

Alloprevotella,

Haemophilus,

Paraprevotella,

Sutterella,

Prevotella,

Barnesiella,

Butyricimonas

 154
PD Patients with PD (n = 80)

Genus:

Parabacteroides,

Verrucomicrobia,

Akkermansia,

Butyricimonas,

Enterococcus,

Lactobacillus,

Bilophila,

Mucispirillum,

Odoribacter,

Veillonella

Genus:

Prevotella

 155
PD Canadian patients with PD (y = 59–71, n = 197)

Family:

Christensenellaceae,

Desulfovibrionaceae

Genus:

Bifidobacterium,

Collinsella,

Bilophila,

Akkermansia

Family:

Lachnospiraceae,

Genus:

Roseburia,

Faecalibacterium

 156
PD Italian patients with PD (mean age = 71.39, n = 64)

Phylum:

Proteobacteria,

Verrucomicrobia,

Actinobacteria

Family:

Verrucomicrobiaceae,

Bifidobacteriaceae,

Streptococciaceae,

Desulfohalobiaceae

Genus:

Akkermansia,

Escherichia,

Streptococcus,

Clostridium,

Bifidobacterium

Phylum:

Bacteriodetes

Family:

Bacteroidaceae,

Lachnospiraceae,

Brevibacteriaceae,

Sphingobacteriaceae

Genus:

Bacteroides,

Blautia,

Lachnospira,

Roseburia,

Coprococcus

 157
Depression Chinese patients with depression (n = 46)

Phylum:

Bacteroidetes,

Proteobacteria

Family:

Bacteroidaceae,

Enterobacteriaceae,

Porphyromonadaceae,

Rikenellaceae

Genus:

Alistipes,

Bacteroides,

Parabacteroides,

Phascolarctobacterium,

Roseburia

Phylum:

Firmicutes,

Fusobacteria,

Actinobacteria

Family:

Lachnospiraceae,

Ruminococcaceae,

Veillonellaceae

Genus:

Escherichia/Shigella,

Oscillibacter,

Dialister,

Faecalibacterium,

Prevotella,

Ruminococcus

 158
Depression Chinese patients with depression (n = 165)

Phylum:

Bacteroidetes

Family:

Bacteroidaceae,

Veillonellaceae,

Lachnospiraceae

Genus:

Bacteroidetes

Family:

Enterobacteriaceae,

Pseudomonadaceae,

Ruminococcaceae,

Christensenellaceae

 159
Anxiety Chinese patients with anxiety (n = 36)

Order:

Betaproteobacteriales,

Enterobacteriales

Family:

Bacteroidaceae,

Enterobacteriaceae

Genus:

Bacteroides,

Escherichia/Shigella,

Phylum:

Firmicutes

Family:

Prevotellaceae,

Genus:

Dialister,

Subdoligranulum,

Megamonas,

Acinetobacter

 160
Anxiety Chinese patients with anxiety (n = 40)

Phylum:

Fusobacteria,

Bacteroidetes

Genus:

Fusobacterium,

Ruminococcus gnavus,

Bacteroides

Phylum:

Firmicutes

Genus:

Lachnospira,

Butyricicoccus, Sutterella,

Eubacterium rectale,

Faecalibacterium

 161

Abbreviation: aMCI, amnestic mild cognitive impairment.