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. Author manuscript; available in PMC: 2024 Jul 21.
Published in final edited form as: Nat Struct Mol Biol. 2023 Dec 7;31(6):910–924. doi: 10.1038/s41594-023-01184-4

Extended Data Fig. 7. AlphaFold Multimer prediction of CCDC22-CCDC93 binding to COMMD.

Extended Data Fig. 7.

(A-C) Overlays of AlphaFold Multimer models and schematic showing CCDC22-CCDC93 binding to COMMD decamer ring for proteins from Human (A), Zebrafish (B), and Amoeba (Dictyostelium) (C). (D-F) Representative AFM models colored using pLDDT scores. (G-I) PAE score matrices of the AFM models shown in (D-F). Boundaries of protein sequences and important structure regions are indicated.