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. Author manuscript; available in PMC: 2024 Jul 21.
Published in final edited form as: Lancet. 2022 Sep 5;400(10356):921–972. doi: 10.1016/S0140-6736(22)01273-9

Table 5:

Standard investigations when patients with chronic obstructive pulmonary disease seek medical attention for suspected disease exacerbation

Essential Dependent on context or presentation
Inflammation and infection
Full blood count X
C-reactive protein or procalcitonin X
Airway microscopy and culture X
Airway cytology (eosinophils) X
Airway molecular testing for pathogens X
Fractional exhaled nitric oxide X
Hypoxia, hypercapnia, and metabolic status
pH of venous blood gas X
Arterial oxygen saturation X
General physiology
Breathing rate X
Electrocardiography X
Lung function X
Imaging
Chest radiography, ultrasonography, or CT X
Systemic measurements
D-dimer X
Renal function X
Troponin X
B-type natriuretic peptide X