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. 2024 Jun 26;52(13):7720–7739. doi: 10.1093/nar/gkae540

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© The Author(s) 2024. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — KSHV lytic transcriptome resolved by TRIMD. (A–C) Identification of novel and previously annotated TSSs (A), splice junctions (B) and polyadenylation sites (C) by TRIMD analysis of KSHV lytic transcriptome from 48 h induced BCBL-1 cells. The inner circles display the numbers of each feature represented in the complete full-length transcript isoforms validated by TRIMD. (D) An integrated genome viewer (IGV) snapshot of TRIMD-identified KSHV transcripts (lower panel) mapped to the KSHV reference genome (NC_009333.1) (top panel). The figure is limited to display the most comprehensive view on IGV (maximum zoom-out), and complete details of transcriptome are provided in Supplementary Table S3.