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. Author manuscript; available in PMC: 2024 Aug 1.
Published in final edited form as: Am J Prev Med. 2024 Feb 16;67(2):303–310. doi: 10.1016/j.amepre.2024.02.009

Table 1.

Effectiveness of Digital Health Interventions to Increase PrEP Adherence

Outcome Measure Number of Studies Effect Sizes
Good adherencea 6 Absolute difference:
   Median: 13.0 pct pts (IQId: 6.4 - 25.3 pct ptse)
Relative difference:
   Median: 19.3% (IQId: 9.0 - 40.0%)
Excellent adherenceb 4 Absolute difference:
   Median: 16.8 pct pts (IQId: 12.7 - 26.7 pct ptse)
Relative difference:
   Median: 75.5% (IQId: 12.7 - 26.7%)
Retentionc 1 ORf: 2.62 (95% CI 1.24 - 5.54; p=0.01)

Note: Boldface indicates statistical significance (p<0.05)

a

Good adherence: consistent with four or more doses of PrEP per week

b

Excellent adherence: consistent with 7 doses of PrEP per week

c

Retention: proportion of participants making all clinical visits

d

IQI: interquartile interval

e

Pct pts: percentage points

f

OR: odds ratio