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Multivariate analysis of factors affecting OS in MPN-AP/BP
| Variable | HR (95% CI) | P value |
|---|---|---|
| Age ≥ 65 y | 1.870 (1.265, 2.765) | .002 |
| WBC > 25 × 109/L | 2.354 (1.589, 3.488) | < .0001 |
| Platelet > 100 × 109/L | 0.443 (0.272, 0.723) | .001 |
| Hemoglobin > 10 g/dL vs < 8 g/dL | 0.629 (0.425, 0.929) | .02 |
| TP53 mutation status | 2.146 (1.460, 3.153) | .0001 |
| Splenomegaly | 1.305 (0.925, 1.842) | .13 |
