GATA6+ serous cavity macrophages uniquely respond to inflammatory stimuli in vitro
(A) Co-localization of major integrin dimers of pericardial macrophages (top) and myocardial macrophages (bottom).
(B) Histograms showing expression of integrin monomers on pericardial and myocardial macrophages.
(C) Schematic of in-vitro experiments.
(D) CCL2 mRNA fold change in macrophages (n = 3 for all groups).
(E) CCL11 mRNA fold change in macrophages.
(F) CxCL9 mRNA fold change in macrophages.
(G) IL-1β mRNA fold change in macrophages.
(H) CCL2 mRNA fold change in fibroblasts.
(I) CCL11 mRNA fold change in fibroblasts.
(J) GM-CSF mRNA fold change in fibroblasts.
(K) α-SMA mRNA fold change in fibroblasts. Statistics: for macrophages two-way ANOVA with Tukey’s multiple comparisons test was used. For fibroblasts one-way ANOVA with Tukey’s post-test was used. Lines between groups represent the result of Tukey’s post-test. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001.