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. 2024 Jun 27;47:191–206. doi: 10.1016/j.jot.2024.06.009

Table 1.

Electroactive biomaterials in the application of bone healing.

Electroactive biomaterial Category Pros Cons Ref.
BT Piezoelectric/ferroelectric ceramic High piezoelectric coefficiency, good biocompatibility and negligible cytotoxicity Poor degradability, brittle and poor processibility [[23], [24], [25], [26]]
ZnO Piezoelectric metal oxide Excellent biodegradability, antibacterial Dose dependent cytotoxicity [[27], [28], [29]]
PVDF Piezoelectric/ferroelectric polymer High flexibility and stiffness, similar elastic modulus to cancellous bone Poor biodegradability, potential hear failure risk [30,31,32]
PLA/PLLA Piezoelectric polymer Good biocompatibility and biodegradability Unstable electrical power, weak mechanical property [33,[34], [35], [36]]
CNT/GO Carbon-based conductive material Great mechanical property, large surface area, high conductivity Low biodegradability, dose-dependent cytotoxicity, poor dispersion [37,38,39,40,41]
PPy/PANi/PEDOT Conductive polymer Commercial convenience, good processibility Low biodegradability, poor dispersion [42,43,[44], [45], [46], [47],48]
Ag/Au nanoparticles Conductive metal Robust mechanical property, high conductivity, antibacterial Expensive, low biodegradability [40,[49], [50], [51], [52], [53],54]