Putrescine supplementation lowers EcNC101 colonization and tumor development in the AOM/DSS colorectal cancer mouse model. A, Study design. B, EcNC101 abundance at the endpoint was assessed by CFUs (log-scale representation). C, Body weight variation of mice throughout the experiment (mean ± SEM; repeated-measure ANOVA, post hoc Tukey; *, P < 0.01, between the groups). D, Representative pictures of the colon and quantification of the colon length. Colonic (E) tumor count and (F) tumor size. ANOVA, post hoc Tukey; *, P < 0.05, between EcNC101 WT and EcNC101 ΔclbP of the same treatment group; N = 8–9 per group.