Skip to main content
. Author manuscript; available in PMC: 2024 Nov 1.
Published in final edited form as: Heart Fail Rev. 2023 Aug 30;28(6):1297–1306. doi: 10.1007/s10741-023-10337-y

Table 4.

Listing criteria for heart transplantation based on cardiopulmonary exercise test data from the International Society for Heart Lung Transplantation

Condition Criteria
Beta-adrenergic blockade Peak VO2 ≤ 12 mL·kg−1·min−1
No beta-adrenergic blockade Peak VO2 ≤ 14 mL·kg−1·min−1
< 50 years and women In addition to peak VO2 ≤ 12 (or 14) mL·kg−1·min−1, consider peak VO2 < 50% predicted
Peak respiratory exchange ratio < 1.05 VE/VCO2 slope > 35 may be considered
Obese (body mass index > 30 kg·m−2) Consider lean body mass–adjusted peak VO2 < 19 mL·kg−1·min−1

VE minute ventilation, VCO2 volume of carbon dioxide exhaled, VO2 volume of oxygen uptake. Adapted from Mehra et al. [1]