Table 3.
Imaging features on MR and molecular subtypes of breast cancer.
| Imaging features | Total n=112 | Luminal A (n=16) | Luminal B HER2- (n=59) | Luminal B HER2+ (n=14) | HER2 (n=12) | Triple Negative (n=11) |
|---|---|---|---|---|---|---|
| Type | ||||||
| Mass | 98(87.5) | 10(62.5) | 56(94.9) | 13 (92.9) | 8 (66.7) | 11(100) |
| Non-mass enhancement | 14(12.5) | 6(37.5) | 3(5.1) | 1 (7.1) | 4 (33.3) | 0 |
| p | 0.005a | 0.02b | 1.000b | 0.043b | 0.353b | |
| Shape of mass(n=98) | ||||||
| Round/Oval | 28(28.6) | 7(70) | 15(26.8) | 2(15.4) | 3(37.5) | 5(45.5) |
| Irregular | 70(71.4) | 3(30) | 41(73.2) | 11(84.6) | 5(62.5) | 6(54.5) |
| p | 1.000b | 0.822a | 0.338b | 0.685b | 0.268a | |
| Margin of mass (n=98) | ||||||
| Circumcribed | 4(4.1) | 0 | 2(3.6) | 0 | 0 | 2(18.2) |
| Irregular | 57(58.2) | 7(70) | 31(55.4) | 7(53.8) | 6(75) | 6(54.5) |
| Spiculated | 37(37.7) | 3(30) | 23(41.1) | 6(46.2) | 2(25) | 3(27.3) |
| p | 0.829b | 0.672b | 0.866b | 0.627b | 0.116b | |
| Distribution of non-mass enhancement(n=14) | ||||||
| Focal/linear | 3(21.4) | 3(5 0) | 0 | 0 | 0 | 0 |
| Segmetal/regional/ diffuse | 11(78.6) | 3(50) | 3(100) | 1(100) | 4(100) | 0 |
| p | 0.055b | 1.000b | 1.000b | 0.505b | ||
| Other features (n=112) | ||||||
| Edema | 24(21.4) | 2(12.5) | 10(16.9) | 3(21.4) | 2(16.7) | 7(63.6) |
| p | 0.515b | 0.255a | 1.000b | 1.000b | 0.002b | |
| Unifocal | 49 (43.8) | 8(50) | 25(42.4) | 4(28.6) | 3(25) | 9(81.8) |
| p | 0.786a | 0.849a | 0.261b | 0.224b | 0.010b | |
| Adenopathy | 62(55.4) | 10(62.5) | 29(49.2) | 9(64.3) | 8(66.7) | 6(64.5) |
| p | 0.596a | 0.186a | 0.572a | 0.543b | 1.000a | |
| Distortion | 19(17) | 1(6.25) | 11(18.6) | 1(7.1) | 5(41.7) | 1(9.1) |
| p | 0.3b | 0.802a | 0.458b | 0.03a | 0.687b | |
| T2W | ||||||
| Hypo/Iso-intensity | 60(53.6) | 14(87.5) | 32(54.2) | 8(57.1) | 5(41.7) | 1(9.1) |
| Hyperintensity | 52(46.4) | 2(12.5) | 27(45.8) | 6(42.9) | 7(58.3) | 10(90.9) |
| p | 0.005b | 1.000a | 1.000a | 0.542a | 0.003a | |
| DWI | ||||||
| Restricted | 104(92.9) | 12(75) | 56(94.9) | 13(92.9) | 12(100) | 11(100) |
| Non-restricted | 8(7.1) | 4(25) | 3(5.1) | 1(7.1) | 0 | 0 |
| p | 0.014b | 0.473b | 1.000b | 0.596b | 1.000b | |
| Initial phase | ||||||
| Fast | 59(52.7) | 8(50) | 24(40.7) | 9(64.3) | 10(83.3) | 8(72.7) |
| Slow/Medium | 53(47.3) | 8(50) | 35(59.3) | 5(35.7) | 2(16.7) | 3(27.3) |
| p | 1.000a | 0.008a | 0.403a | 0.032b | 0.211b | |
| Late phase | ||||||
| Type 2/3 | 103(92) | 13(81.3) | 55(93.2) | 13(92.9) | 12(100) | 10(90.9) |
| Type 1 | 9(8) | 3(18.7) | 4(6.8) | 1(7.1) | 0 | 1(9.1) |
| p | 0.118b | 0.733b | 1.000b | 0.594b | 1.000b | |
| Enhancement morphology | ||||||
| Rim enhances | 40(35.7) | 1(6.3) | 18(30.5) | 5(35.7) | 6(50) | 10(90.9) |
| Non-rim enhances | 72(64.3) | 15(93.7) | 41(69.5) | 9(64.3) | 6(50) | 1(9.1) |
| p | 0.009b | 0.242a | 1.000a | 0.343a | 0.000b | |
Values are given as no. (%); mean±standard deviation.
a
Chi’s square test.
b
Fisher’s Exact Test.